A Master's thesis titled "Preparation and evaluation of the biological activity of some oxadiazoline derivatives" was successfully defended by student Ali Mousa Abd at the College of Pharmacy.
The research focused on the synthesis of nine novel oxadiazoline compounds via the cyclization of nicotinic acid hydrazone derivatives. Chemical structures were analytically confirmed using Infrared (IR), 1H-NMR, and 13C-NMR spectroscopy. Furthermore, the laboratory evaluated the antimicrobial efficacy of these compounds against various bacterial and fungal strains.
The study concluded that these newly synthesized derivatives demonstrate significant potential as effective antimicrobial agents. This achievement paves the way for developing advanced antibiotics specifically designed to combat the rising challenges of multi-drug resistant bacterial and fungal infections.
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