A research team from the College of Pharmacy, including Assistant Professor Dr. (Iman Tariq Ali), Assistant Professor Dr. (Maitham Abdel-Nabi), and Researcher (Ghasaq Mohammed Muhaibal), published specialized research in the Polish journal "Onkologia i Radioterapia," indexed in Scopus.
The research, titled "Correlation between PD-L1 expression, demographic and pathological characters in patients with breast cancer," studied the correlation between serum levels of Programmed Death-1 (PD-1) and its ligand (PD-L1) with the demographic and clinicopathological characteristics of breast cancer patients. The study aimed to evaluate these serum markers alongside Interferon Gamma (IFN-γ) and Cancer Antigen 15-3 (CA 15-3) to provide an integrated database for future immunotherapy applications.
This study is the first of its kind in Iraq to address these specific immune checkpoints. The results showed significant correlations between these protein levels and age, family history, tumor size, and lymph node status in the pre-treatment group. The research significance lies in providing a better understanding of the predictive value of these proteins, helping identify patients who would benefit most from modern immunotherapy protocols.
This scientific achievement underscores the University of Basrah's commitment to supporting high-impact medical research that contributes to developing personalized treatment strategies in line with global cancer trends.
UNIVERSITY OF BASRAH | CLINICAL BIOCHEMISTRY | CANCER RESEARCH UNIT
© 2024 Global Academic Publication
