Researcher (Wafaa Youssef Khalaf) defended her thesis titled "Synthesis, characterization, molecular docking study, and biological evaluation of new coumarin-pyrazoline derivatives."
Methodology & Characterization:
The study involved the synthesis of two groups of derivatives (Coumarin chalcone and Coumarin pyrazoline), characterized using advanced spectral analyses including Infrared (IR), Mass Spectrometry, Nuclear Magnetic Resonance (NMR), and UV-Visible spectroscopy.
The research aimed to explore the biological activity of these compounds using advanced molecular docking software and biological cell experiments. The study concluded that these derivatives possess effective antioxidant properties.
In the context of oncology research, results showed limited biological activity against the specific breast cancer cell line (MCF7), paving the way for future studies to enhance the structural properties and therapeutic efficacy of these compounds.
UNIVERSITY OF BASRAH | PHARMACEUTICAL CHEMISTRY | MASTER'S DEFENSE
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