Candidate: Zeina Abdul-Ali Jaber
Thesis Title: Preparation, characterization, and microbiological evaluation of new drug derivatives from crown ethers.
Methodology & Experimental Results
The study focused on the functional activation of dibenzo-18-crown-6-ether to synthesize alpha-beta unsaturated ketone (chalcone) compounds through chemical reactions with aromatic aldehydes. These derivatives possess potent pharmacological properties as antibacterial and antifungal agents, showing significant efficacy when compared to standard antibiotics.
Future Therapeutic Significance:
The scientific value of this research lies in the development of new drug molecules that may serve as effective alternatives to conventional antibiotics, particularly in combating resistant bacterial infections. This study enhances the potential for diversifying pharmaceutical compounds with higher efficacy for broad therapeutic uses.
UNIVERSITY OF BASRAH | COLLEGE OF PHARMACY | PHARMACEUTICAL SCIENCES
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