Master's Thesis at the College of Pharmacy Explores Naproxen Derivatives as Potential Anti-Tumor Agents
The College of Pharmacy at the University of Basrah discussed a Master's thesis investigating new Aryl Schiff bases of Thiadiazole derivatives as DNA binding agents and potential anti-tumor candidates.
The thesis, presented by student Amer Abdul Karim Jaab, involved the synthesis of innovative Thiadiazole Schiff base derivatives and evaluated their selective activity against breast cancer cells. The findings revealed that one of the synthesized compounds exhibited significant efficacy with superior selectivity compared to normal cells.
The research methodology focused on modifying the conventional "Naproxen" drug—typically used as an anti-inflammatory and analgesic—by integrating specialized chemical groups to grant it anti-cancer properties. These results open new avenues for testing these derivatives against various other types of tumors, marking a qualitative addition to pharmaceutical chemistry.








