Master's Thesis Discusses Improving Bioavailability of Ticagrelor Using Nanotechnology

Formulation, characterisation and evaluation of ticagrelor loaded nanomicelles for enhancement of oral bioavailability

The College of Pharmacy at the University of Basrah conducted the defense of the Master's thesis by student **Zainab Fadhil Abbas**, which explored the use of Nanomicelle technology to prepare advanced nano-carriers capable of improving the intestinal absorption of **Ticagrelor**.

• **Novel Permeability Technique:** The study is the first to utilize a highly precise drug absorption testing technique using small rat intestinal segments.
• **Chemical Stability:** Nanomicelles demonstrated high stability within both acidic gastric and neutral intestinal environments, maintaining properties during 3 months of storage.
• **Enhanced Absorption:** Results indicated significantly higher permeability for Ticagrelor when formulated as Nanomicelles compared to conventional methods.