Dr. Mohammed Sabbar, a teacher at the Faculty of Pharmacy, published a paper entitled "Preparation and Characterization" Dumbredone nanoparticles to improve melting) in the Iraqi Journal of Pharmaceutical Sciences. Where Dr. Mohammed Sabbar explained that the study was conducted to prepare and characterize nanoparticles For domperidone to increase its melting and increase the speed of the release of the drug. Dumbredon is the opposite of dopamine. It is used as an anti-nausea and vomiting, and dombrydone is insoluble in water and suffers from a deficiency Bioavailability from 13-13%. The nanoparticles of dumbredone were prepared by a method Solvent deposition/ anti-solvent using different ratios of polymer: ratios 3:1 and 3:3 of Polymer for polymer and polymers (HPMC-E50, HPMC-E15, CMC-30, PVP- K30, PVP-K15) as stabilizers. The effect of the polymer type and its concentration and the ratio of the solvent to the anti Solvent, speed and time of stirring on the size of nanoparticles by measuring particle size Its surface area and particle distribution coefficient. Dr. Mohammed Sabbar explained that the research My application in the manufacture of domperidone is characterized by the release of a drug better than made globally.