Basrah - College of Pharmacy Media:

A Master's thesis at the College of Pharmacy at the University of Basrah discussed "The Synthesis, Characterization, and Study of the Antibacterial Activity of New Compounds from 1,3,4-Oxadiazole Derivatives."

The thesis, presented by student Suhail Hussein Jawad, consisted of three chapters. The first chapter included an introduction to the thesis topic and a scientific literature review. The second chapter covered the methods of synthesizing the compounds, while the third chapter included a detailed presentation, characterization, and discussion of the results.

The thesis aimed to synthesize a new series of Oxadiazole compounds and measure their antibacterial activity against two types of bacteria (Gram-positive and Gram-negative). The chemical structure of the synthesized compounds was characterized through physicochemical properties, accurate spectrophotometric and quantitative analysis, as well as Nuclear Magnetic Resonance (NMR).

The study concluded that some of the synthesized compounds exhibited antibacterial activity, and that some of these compounds containing polar groups showed good results against resistant bacteria when using different concentrations of the synthesized compounds. The results were compared with standard drugs, namely Amoxicillin and Cefepime.

❧ ☙