A Master's thesis at the College of Pharmacy, University of Basrah, examined "A Study on the Phytochemical Properties of Phenolic Compounds (Cinnamic Acid and its Derivatives) in the Caper Plant in Basrah and the Evaluation of their Biological Activity." The thesis, presented by the student Mohammed Abdul Mahdi Nema, involved a comprehensive research study on the caper plant collected from southern Basrah.
One of the notable phenolic compounds, cinnamic acid, was successfully extracted from various parts of the plant. The substance was chemically modified to synthesize a novel compound—achieved for the first time globally—by modifying it with fluconazole derivatives. The synthesized substance was tested for its bioactivity, displaying exceptionally high results when compared to standard materials. The study aimed to extract cinnamic acid from different parts of the caper plant, accurately diagnose and isolate the substance using various analytical instruments, chemically modify it, and comprehensively test and evaluate its biological activity.
The study concluded with the successful extraction of phenolic compounds from the caper plant and the triumphant discovery and isolation of cinnamic acid. Furthermore, the extracted substance was rigorously tested for its robust antioxidant properties and potent biological efficacy against several strains of pathogenic bacteria and fungi.
