A Master's thesis at the College of Pharmacy, University of Basrah, examined "A Study of Some Pharmacological Effects of Chlorophyllin on Oxidative Stress Induced by the Use of Indomethacin in Rats". The thesis, presented by the student Ibrahim Hashim Muslim, aimed to explore the properties of sodium copper chlorophyllin, including its gastric absorption and its effect on intestinal motility in rats, in addition to its effects on gastric acidity levels and its efficacy in reducing the dimensions of gastric ulcers.
The thesis included an investigation into the therapeutic role of sodium copper chlorophyllin against indomethacin-induced gastric ulcers in rats, utilizing fifty adult rats for the study. The research concluded that the groups treated with sodium copper chlorophyllin exhibited a significant reduction in gastric acidity and successfully restored normal acidity levels.
Furthermore, the gastric ulcers induced by indomethacin were confirmed through both macroscopic and microscopic observations. The study highly recommended the therapeutic application of sodium copper chlorophyllin in alleviating indomethacin-induced injuries, given its remarkable therapeutic capacity in treating the indomethacin-induced gastric ulcer model in rats.
